E.B. White’s story of a family whose son happens to be a mouse is lovingly Hollywood-ized. In other words, it bears very little relationship to the book but has a lot of great special effects. Fans of the book will do well to stay at home and re-read it, but families looking for some good action scenes, appealing characters, and a wise-cracking cat will enjoy it very much.

Mr. and Mrs. Little (Hugh Laurie and Geena Davis) drop son George (Jonathan Lipnicki) off at school on their way to the orphanage to adopt a child. They fall in love with Stuart (voice of Michael J. Fox), who is charming, insightful, unselfish — and a mouse. Despite warnings against “inter-species” adoption, they bring him home.

George is disappointed. He does not see how Stuart will ever be able to play with him. And maybe he is a little more jealous than he was expecting. He insists, “He’s not my brother — he’s a mouse!”

But that is nothing compared to the ferocious resentment of another member of the Little family — Snowball the cat. Snowball (hilariously voiced by Nathan Lane) is furious at being told that “we don’t eat family members,” and humiliated at having a mouse as “an owner.” He plots to get rid of Stuart.

Stuart manages to surmount the literally enormous obstacles of a world way out of proportion. He even wins over George, after he demonstrates his courage and loyalty in a boat race in Central Park. But he still feels an emptiness inside, and wonders about his birth parents.

Then two mice show up claiming to be his birth parents. Stuart realizes that the Littles are his real family. “You don’t have to look alike. You don’t even have to like each other.” Your family are the people who stick with you. His home is where they are.

This is a terrific family movie. Stuart, created entirely through computer graphics, is perfectly integrated into the live action. And I do mean action — the boat race and chase sequences are among the most exciting on screen this year. The script by the screenwriter/director of “The Sixth Sense” does not talk down to kids and has some genuine insights about sibling rivalry, the fear of failure, and family.

It is worth noting that this movie had by far the most enthusiastic audience reaction of any I saw this year, with shrieks of joy when Snowball went into the trash can and cheers at the boat race and chase scenes. I have to admit, I felt like cheering myself.

Parents should know that the movie is rated PG for brief mild language and scenes of peril.

Adoptive and foster families may want to think carefully about whether the themes will be upsetting or reassuring to their children. They should prepare adopted or foster children before they see the movie. They can emphasize the way that the Littles selected Stuart because they could tell he was right for them, and they should make it clear (if appropriate) that they would never let anyone take their children away. Like Stuart, they can explain that they recognize that families are people who stick up for each other. In the movie, it was not just Stuart who learned that lesson — the Littles also learned that they were wrong in thinking that Stuart would be happier with mice than with people.

All families who see this movie should talk about what makes people feel that they “fit in,” about jealousy and the way it makes us think that hurting others will help us feel better (but it doesn’t), and the importance of Mr. Little’s advice about trying — and George’s success in reminding him about it at the right moment.

Families who enjoy this movie will also enjoy another movie based on a book by E.B. White, “Charlotte’s Web.”