Top voice talent and good 3D computer graphics cannot make up for the fact that this film is utterly synthetic as well as crass, loud, and vulgar. Even at a brief running time of under 90 minutes, it overstays its welcome.

A team of super-agent guinea pigs, assisted by a reconnaissance fly and a computer whiz mole (Nicolas Cage), fail in a mission to find out what weapons-dealer-turned-consumer-electronics mogul Saber (Bill Nighy) is up to. So, over the protests of their human leader, Ben (Zach Galifianakis), the program is shut down by the FBI’s Kip Killian (Will Arnett). The guinea pigs and mole have to escape from a pet shop — and from children who abuse them — to prevent Saber’s diabolical plot from being executed.

The script is predictable and derivative. References to other movies like “Die Hard” and “Scarface” may amuse parents and potty jokes may amuse children but they contribute to a crass and lazy feel to the film. The 3D effects are mostly used to make the audience duck flying glass shards and spraying water. If they’re smart, they’ll just duck the movie.